GABAA receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts
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چکیده
منابع مشابه
The anxiolytic effects of a Valerian extract is based on Valerenic acid
BACKGROUND Valerian is commonly used for the treatment of insomnia and anxiety. Valerian extracts allosterically modulate GABA-A receptors and induced an anxiolytic activity. This activity is closely related to valerenic acid. In the present experiments it was investigated whether acetoxy valerenic acid may interfere with the anxiolytic action of valerenic acid. METHODS Situational anxiety wa...
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ژورنال
عنوان ژورنال: Neuropharmacology
سال: 2009
ISSN: 0028-3908
DOI: 10.1016/j.neuropharm.2008.06.013